Second Brains: Enteric Nervous Systems Across Phylogeny

Enteric nervous systems can be found in organisms lacking a discernable brain, leading to speculation that the enteric nervous system is, in fact, an evolutionary innovation predating the CNS. Despite striking features, there are marked gaps in understanding the cellular composition of enteric nervous systems, the terminal differentiation of enteric neurons, their assembly into functional circuitry, their plasticity, and their interaction with other organs and the environment. This conference brings together a diverse set of nascent and established experts addressing these questions, using a combination of approaches in a variety of systems (jellyfish, worms, flies, fish, mice and humans). Topics will include the cellular and functional diversity of enteric neurons, the genetic programs that instruct their terminal identities, and their integration into functional circuitry. We will discuss how enteric neurons not only control gut function, but how they also receive and send signals to other parts of the body, namely the immune system, and their interactions with the microbiome. By considering enteric nervous systems in a wide variety of invertebrate and vertebrate species, we look forward to conversations about core conserved features and their evolutionary history. In bringing together field experts, we aim to foster a sense of community, promote collaborations and cross-fertilize experimental approaches.

Janelia will cover lodging and meals for all participants, and travel support is available to those in need (please indicate need in that portion of the application). Participants are expected to stay for the duration of the meeting.

The meeting will begin at 6pm ET on the first day and end by 1pm ET on the last.

Applications are closed.

Please note: Because Janelia conferences are intentionally small and selective, we may not be able to accommodate all applicants. We strive for as broad a representation across labs as possible and therefore may limit participation to one person per group. Preference is given to applicants who are active researchers in the field and intend to present their work as a poster or selected talk.